Academic Research

Associated Labs

• Segura Laboratory, Duke University

• Drug Discovery and Development Laboratory, Villanova University

• Biochemical Engineering and Bioprocessing Laboratory, Villanova University

Research Topics/Projects

• Scaffold-based non-viral gene delivery in granular hydrogels for tissue repair (2018-2023)

  • • Gene Delivery From Granular Scaffolds for Tunable Biologics Manufacturing (2024)

    • Nucleic acid-loaded granular hydrogel scaffolds for sustained and localized gene delivery to enhance tissue repair

    • Stabilized dendrimer-lipid mRNA nanoparticles for direct and hydrogel-mediated gene delivery

• Ex Vivo T-Cell Growth, Capture, Characterization, and Modification in WAVE Bioreactors for CAR T-Cell Therapy (2017-2018)

• Synthetic Production of Plasmids for Gene Therapy (2017)

• Small Molecule Inhibition of the Innate Immune Response Increases Transgene Expression (2017)

  • • Enhancement of Transgene Expression by Caffeic Acid and Chlorogenic Acid (2016)

ORCID